O-095 Different phenotypes of PCOS: Implications to clinical practice

Abstract Polycystic ovary syndrome (PCOS) is a very common, heterogeneous which presents with spectrum of clinical and biochemical features. It associated both reproductive metabolic dysfunction has negative impact on long term health, including mental health. Although there appears to be common genetic background PCOS, regardless presentation, environmental factors, diet, play an important part in determining the phenotype. The most commonly used diagnostic criteria, Rotterdam takes account heterogenous nature but presentation can categorised as four subtypes comprise (A) ovulatory dysfunction, hyperandrogenism, polycystic ovaries (PCO), (B) hyperandrogenism without PCO, (C) PCO (D) hyperandrogenism. These are not rigid categories since some women may go from one another, for example weight gain lead anovulation woman who previously had hirsutism regular cycles. Nevertheless, sub-category significance influence management. Women have (A&B) at higher risk exacerbated by obesity (and carries high long-term diabetes cardiovascular disease) so merit thorough investigation includes assessment glucose tolerance lipids. Those predominantly problems require fertility treatment or regulation menses simply irregular need no specific treatment. Symptoms (hirsutism, acne, alopecia) particularly distressing best managed collaboration dermatologist. PCOS health problem, prevalence only recently been appreciated. Not surprisingly, it relevant those moderate severe symptoms In summary, characterised variety endocrine abnormalities tailor individually, according symptom relief regard concerns about